1883 – Professor Charles Richardson
1887 – William F. Gorrie
1889 – General William Henry Harrison Beadle
1901 – Professor William W. Girton (Interim)
1902 – General William Henry Harrison Beadle
1905 – John W. Heston
1920 – Bela Malcolm Lawrence (Acting, February – July)
1920 – Edgar C. Higbie
1931 – F.A. Bixler (Acting)
1933 – Vayne Arnold Lowry
1962 – Dr. Laurence Samuel Flaum
1967 – Harry Pitkin Bowes
1971 – Dr. Allen R. Millar
1972 – Dr. Francis Gordon Foster
Dakota State College was a branch of University of South Dakota from 1974-78.
1974 – Dr. Richard Bowen
1977 – Dr. Charle Lein
1978 – Dr. Carleton M. Opgaard
1983 – Charles Luke
1984 – Dr. Richard J. Gowen
1987 – Dr. Jeral A. Tunheim
2004 – Dr. Douglas D. Knowlton
2012 – Dr. David B. Borofsky
2014 – Dr. Marysz Rames (Interim)
2015 – Present – Dr. José Marie Griffiths